Abstract: Charles Bonnet syndrome (CBS) is a kind of visual hallucination disease secondary to visual impairment. Patients generally have complete insight and no mental disorder. The prevalence of CBS is quite low, and it is more common among the elderly. Its pathogenesis remains unclear, but there are well-recognized theories, such as release phenomenon and deafferentation theory. At present, there is no unified diagnostic criteria for CBS, the diagnosis and differential diagnosis are mostly based on clinical features. The main goal of treatment is to restore vision. Ophthalmic treatment is the first choice. (Int Rev Ophthalmol, 2022, 46: 516-522)

Key words: Charles Bonnet syndrome, visual hallucination